[PDF][PDF] Nuclear FAK promotes cell proliferation and survival through FERM-enhanced p53 degradation

…, XL Chen, Y Lim, DA Hanson, TT Vo, K Howerton… - Molecular cell, 2008 - cell.com
FAK is known as an integrin- and growth factor-associated tyrosine kinase promoting cell
motility. Here we show that, during mouse development, FAK inactivation results in p53- and …

Identification and characterization of repopulating spermatogonial stem cells from the adult human testis

…, J Pacchiarotti, T Ramos, K Howerton… - Human …, 2011 - academic.oup.com
BACKGROUND This study was conducted to identify and characterize repopulating
spermatogonial stem cells (SSCs) in the adult human testes. METHODS Testes biopsies from …

Differentiation potential of germ line stem cells derived from the postnatal mouse ovary

J Pacchiarotti, C Maki, T Ramos, J Marh, K Howerton… - Differentiation, 2010 - Elsevier
General belief in reproductive biology is that in most mammals female germ line stem cells
are differentiated to primary oocytes during fetal development and oogenesis starts from a …

FAK promotes organization of fibronectin matrix and fibrillar adhesions

…, Q Han, JB Kim, K Howerton… - Journal of cell …, 2004 - journals.biologists.com
Targeted disruption of the focal adhesion kinase (FAK) gene in mice is lethal at embryonic
day 8.5 (E8.5). Vascular defects in FAK -/- mice result from the inability of FAK-deficient …

Generation of multipotent cell lines from a distinct population of male germ line stem cells

…, T Wang, R Gonzalez, T Ramos, K Howerton… - …, 2008 - rep.bioscientifica.com
… To sort for GFP/c-KitC/K cells, first we gated the whole GFP population with the non-stained
cells to establish a baseline for APC channel. A region was placed based on the baseline to …

Comparison of representative ranges based on US patient population and literature reference intervals for urinary trace elements

G Komaromy-Hiller, KO Ash, R Costa, K Howerton - Clinica Chimica Acta, 2000 - Elsevier
Reference intervals for trace elements are very hard to obtain because of the difficulty of
defining a nonexposed reference population. However, representative ranges for trace …

Hair cycle and wound healing in mice with a keratinocyte-restricted deletion of FAK

…, S McDonagh, G Dolganov, K Howerton… - Oncogene, 2006 - nature.com
Focal adhesion kinase (FAK) is a critical component in transducing signals downstream of
both integrins and growth factor receptors. To determine how the loss of FAK affects the …

[HTML][HTML] Developing a clinical-grade cryopreservation protocol for human testicular tissue and cells

…, K Howerton, S Greilach, K Zaragoza… - BioMed Research …, 2013 - hindawi.com
Recent work in preservation of female fertility as well as new information on the nature of
spermatogonial stem cells has prompted an investigation into the possibility of an effective …

Predicted impact of management changes on soil carbon storage for each cropland region of the conterminous United States

MD Eve, M Sperow, K Howerton, K Paustian… - Journal of Soil and …, 2002 - jswconline.org
The exchange of carbon dioxide between the atmosphere, biosphere and pedosphere is an
important consideration when assessing agricultural and environmental management or …

[HTML][HTML] Evaluation of sense-strand mRNA amplification by comparative quantitative PCR

LA Goff, J Bowers, J Schwalm, K Howerton, RC Getts… - Bmc Genomics, 2004 - Springer
… A subset of 192 sequence targets was chosen from the Compugen/Sigma-Genosys Rat 8
K oligo library for qPCR analysis. Using previously-analyzed microarray results as a guide (not …