Context Reflection and reflective practice have become popular topics of scholarly dialogue
in medical education. This popularity has given rise to checklists, portfolios and other tools …

Rationale: Individuals with naturally occurring loss-of-function proprotein convertase
subtilisin/kexin type 9 (PCSK9) mutations experience reduced low-density lipoprotein cholesterol …

Coronaviruses are a family of RNA viruses that cause acute and chronic diseases of the
upper and lower respiratory tract in humans and other animals. Severe acute respiratory …

A series of land-based surveys were conducted at two vantage points of known dolphin
abundance in Hong Kong. The purpose of this study was to determine the behavioral response …

The ABC transporter associated with antigen processing (TAP) shuttles cytosolic peptides
into the endoplasmic reticulum for loading onto class I MHC molecules. Transport is fueled by …

Improving therapeutic delivery to the body will have significant benefits for the treatment of a
variety of diseases. Incorporating drugs inside engineered colloidal carriers is a promising …

IKKϵ is an IKK (inhibitor of nuclear factor κBkinase)–related kinase implicated in virus
induction of interferon-β (IFNβ). We report that, although mice lacking IKKϵ produce normal …

Background Using commercially available television and movies is a potentially effective tool
to foster humanistic, compassionate and person-centred orientations in medical students. …

Vehicular ad hoc networks (VANETs) allow vehicles to generate and broadcast messages
to inform nearby vehicles about road conditions, such as traffic congestion and accidents. …

Tank-binding kinase I (TBK1) plays a key role in the innate immune system by integrating
signals from pattern-recognition receptors. Here, we report the X-ray crystal structures of …